What is the primary therapeutic use of Clonidine in pregnancy?

Clonidine is primarily used for the management of hypertension, especially in situations where traditional antihypertensives may pose risks during pregnancy. It works by stimulating alpha-2 adrenergic receptors in the brain, which leads to a decrease in sympathetic outflow, ultimately resulting in lowered blood pressure. This makes it particularly useful for pregnant individuals who may develop gestational hypertension or preeclampsia, conditions that need careful management to protect both maternal and fetal health.

While clonidine may have secondary uses, such as in the management of pain or anxiety, and some off-label applications, its primary and most recognized role in pregnancy is the effective control of high blood pressure. The safety profile of clonidine has also led to its acceptance as an option in treating hypertensive disorders during pregnancy when necessary.