Which fertility drug regimen may be prescribed to a woman diagnosed with primary ovarian failure?

For a woman diagnosed with primary ovarian failure, the appropriate fertility drug regimen involves the use of estrogens and progestins. This condition is characterized by the ovaries not producing sufficient hormones or eggs, which leads to issues with fertility.

Estrogens help to alleviate symptoms associated with low estrogen levels, such as hot flashes and other menopausal-like symptoms. Meanwhile, progestins are critical for inducing a regular menstrual cycle and preparing the uterine lining for potential implantation of an embryo, should conception occur.

While clomiphene citrate is used to stimulate ovulation in women with ovulatory dysfunction, it would not be effective in cases of primary ovarian failure since the primary issue is the lack of viable eggs rather than problems with the ovulation process. Gonadotropins, which contain hormones that stimulate the ovaries, are also not suitable for primary ovarian failure as they require functional ovaries to be effective. Progesterone only therapy does not address the need for estrogen and is not designed to promote fertility.

Therefore, estrogens and progestins provide the necessary hormonal supplementation in managing primary ovarian failure.